<i>In Silico</i> Modeling of C1 Metabolism
نویسندگان
چکیده
منابع مشابه
Integration of C1 and C2 Metabolism in Trees
C₁ metabolism in plants is known to be involved in photorespiration, nitrogen and amino acid metabolism, as well as methylation and biosynthesis of metabolites and biopolymers. Although the flux of carbon through the C₁ pathway is thought to be large, its intermediates are difficult to measure and relatively little is known about this potentially ubiquitous pathway. In this study, we evaluated ...
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In most organisms, tetrahydrofolate (H(4)folate) is the carrier of C(1) fragments between formyl and methyl oxidation levels. The C(1) fragments are utilized in several essential biosynthetic processes. In addition, C(1) flux through H(4)folate is utilized for energy metabolism in some groups of anaerobic bacteria. In methanogens and several other Archaea, tetrahydromethanopterin (H(4)MPT) carr...
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Bradyrhizobium japonicum, a symbiotic nitrogen-fixing soil bacterium, has multiple gene copies for aromatic degradation on the genome and is able to use low concentrations of vanillate, a methoxylated lignin monomer, as an energy source. A transcriptome analysis indicated that one set of vanA1B, pcaG1H1, and genes for C(1) compound catabolism was upregulated in B. japonicum USDA110 cells grown ...
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To study the role of apoC1 in lipoprotein metabolism, we have generated transgenic mice expressing the human APOC1 gene. On a sucrose-rich diet, male transgenic mice with high APOC1 expression in the liver showed elevated levels of serum cholesterol and triglyceride compared with control mice (5.7 6 0.7 and 3.3 6 2.1 vs. 2.7 6 0.1 and 0.4 6 0.1 mmol/liter, respectively). These elevated levels w...
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Metabolism is a network of chemical reactions catalyzed by enzymes. In a cell, ingested sugars and proteins are metabolized to basic compounds such as amino or fatty acids, and they are used to construct cellular structures in turn. This paper proposes the graph modeling of metabolism. It is possible to describe metabolism as a circulation of atoms by representing all reactions with the chemica...
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ژورنال
عنوان ژورنال: American Journal of Plant Sciences
سال: 2015
ISSN: 2158-2742,2158-2750
DOI: 10.4236/ajps.2015.69144